Biopharma is a world of big rewards, and even bigger risks. Since 1992, biopharma companies have turned to Health Advances for business strategies that help maximize the former while minimizing the latter.
Because healthcare is our sole focus, Health Advances quickly integrates knowledge from a clinical, technical, and business perspective to create strategies that guide your most critical business decisions.
How We Help Your Business
Winning strategies. Real results.
Our Biopharma team of scientists, physicians, and industry experts has a deep working knowledge of the healthcare industry and its stakeholders. We tackle the challenges of drug development, market access, and commercialization. Our teams partner with clients to:
Translate emerging science into compelling products backed by actionable development and commercialization strategies.
Develop go-to-market roadmaps that anticipate the evolving healthcare market
Identify opportunities and implement strategies that maximize the value of franchises and companies
Here are some of the ways our Biopharma team is helping clients drive business value:
Vivek Mittal: “When an emerging biotechnology company with a promising tyrosine kinase inhibitor (TKI) suitable for multiple patient populations needed a strategy to maximize clinical development dollars, Health Advances was the firm of choice.”
Andrew Funderburk: “Health Advances has a depth and breadth of scientific and business experience to understand both the key details and the big picture. We develop effective strategies and see them through. On a recent project, Health Advances assisted our client at every step in building a formidable CNS franchise, from defining a vision to completing a major acquisition.”
Sheela Hegde: “Over the years, we have built an unparalleled wealth of insights and expertise in the diabetes space. When our client needed a global forecast for a Phase 3 diabetes asset in a very aggressive timeline, they came to us because they knew we could deliver a level of market analysis and insight that others could not.”
Gary Gustavsen: “We recently completed a large project for a major biopharma that further validated the need for a globally-orchestrated, but locally-tailored companion diagnostic strategy. The barriers to CDx adoption across markets are unique; every country needs its own set of tactics.”
Wyatt Gotbetter: “For a leading manufacturer of generics and biosimilars, Health Advances helped develop a best-in-class design and strategy for launching an auto injector that will ensure our client exceeds all patient and clinician expectations, offering a top patient experience at better value.”
By Brendan Loftus, Wyatt Gotbetter, and Julia A. Gaebler
In recent years, the growth in U.S. drug spending has become a hot-button issue. Data released in 2017 by the pharmacy benefit manager (PBM) Express Scripts illustrates which drugs account for the increased spending. In 2016, spend on so-called specialty drugs, a class that contains many biologics, grew by over 13 percent, while spend on traditional drugs actually declined by 1 percent. Five of the top 10 earning drug therapies in the U.S. in 2016 were biologics.
Zach Donnell, Divya Harjani, Amanda Sani, Ned Wydysh, and Vivek Mittal
CAR-T cell therapy is currently one of the most exciting areas of clinical research. To create these living therapies, human T cells are genetically modified to express a CAR (chimeric antigen receptor) that has been programmed to target specific antigens found on the surface of cancer cells.
Health Advances Adds BioPharma and Health IT Executives to Senior Leadership Team
Building upon recent additions at the Partner level, Health Advances, LLC has recruited two seasoned healthcare industry leaders, Dean Giovanniello and Greg Chittim, as it continues to broaden and deepen the range of its strategy consulting services. Dean Giovanniello, Vice President, will join the leadership team of Health Advances’ Biopharma practice with a focus on emerging biopharma companies. Greg Chittim, Vice President, will co-lead the Health IT and Digital practice, bringing a mix of technical industry experience in population health analytics and management consulting for biopharma, high tech, and government sectors. These new leaders, along with fifteen colleagues in Health Advances’ senior management, expand and strengthen the leadership team to help continue the firm’s strong record of cross-industry expertise and steady growth as it celebrates its 25th anniversary.
Dean Giovanniello, RPh, joins Health Advances with experience in Commercialization and Launch Excellence in the Emerging Biopharma and Medtech industries. He has expertise in developing go-to-market strategies along with operational plans to support launch decision making across a variety of large and orphan disease segments in the US and EU. Immediately prior to joining Health Advances, Dean was a principal at QuintilesIMS Consulting where he focused on commercialization of assets. He has extensive experience in data sources/analytics, primary and secondary market research to support forecasting as well as commercial strategy informed by P&Ls to drive better decision-making for acquisitions and licensing deals. Prior to this work, Dean was an independent commercial consultant working with start-up companies to optimize their launch planning and execution in a variety of therapeutic areas. He has extensive experience in anti-infectives, CNS, gastroenterology, immunology, metabolic, ophthalmology and oncology. During his twenty-year career on the client side of the business at GlaxoSmithKline and Sepracor/Sunovion, Dean held senior positions in sales and sales management, product management, market research and business development. Over the course of his career, Dean has directed the launch of over 10 NCEs, indications and line extensions in numerous therapeutic areas. His teams were the recipients of multiple CEO awards based on innovative launch programs and sales performance. Dean received a BS in Pharmacy from the Massachusetts College of Pharmacy and Allied Health Sciences and is a Registered Pharmacist in the State of New Jersey. He also received an MBA from Lubin School of Business at Pace University in New York City.
Greg Chittim joins Health Advances with fifteen years of experience in strategy, management consulting, marketing, operations, and technology leadership. A computer engineer and manager by training, Greg’s career has included technical software development and product management; strategic growth consulting to the Fortune 500; product management; B2B marketing and communications; and senior operations leadership. Prior to Health Advances, Greg held multiple senior executive roles at Arcadia Healthcare Solutions, a leader in population health analytics and EHR data integrations serving health systems, accountable care organizations, and health plans nationwide. Greg founded and ran a Strategic Marketing team after an initial round of growth equity and drove company-wide business planning, performance improvement and measurement programs as the Strategic Operations leader. Earlier in his tenure, he was the product director for the core analytics platform and a principal consultant in Arcadia’s legacy consulting business. While at Arcadia, Greg also served as a subject matter expert to the Office of the National Coordinator for HIT on health information exchange (HIE) under the federal HIE, Regional Extension Center, and Beacon Community grant programs. Greg began his career as a case team leader and technical project manager at Monitor Group (now part of Deloitte), serving clients in the biopharma, high tech, and government sectors. Greg holds a Masters of Engineering Management degree from the Thayer School of Engineering at Dartmouth College, a collaborative program with the Tuck School of Business. He holds a BE and BA in Engineering and Computer Science, also from Dartmouth College.
Health Advances Vice President Julia Gaebler, Ph.D. authors guest column this month in Clinical Leader
In the last decade, the healthcare industry has witnessed significant changes, some of which present important challenges to how pharmaceutical companies develop drugs. One such challenge is the shift in influence from the physician to the payer in the adoption of new interventions. This article discusses threats to the traditional model of drug development posed by the increasing influence of payers and considers ways for industry to embrace “value-focused development” to simultaneously adapt to the evolving market and de-risk drug development. To read the full article, please click the link above.
Partner Wyatt Gotbetter Featured Healthcare Speaker at Internet of Things (IoT) Panel
Wyatt Gotbetter joined a panel of executives from digital media, solution development and other industries as the Cornell Club of Boston hosted this event to explore the fast growing Internet of Things. The panel discussing new IoT technologies, their impact on business and consumers and future applications and adoption and Wyatt shared perspectives on how healthcare care sectors are embracing the IoT.
Health Advances Adds to Leadership Team
Today, Health Advances promoted Gary Gustavsen, Wyatt Gotbetter, and Andrew Matzkin to the position of Partner to recognize their outstanding contributions. All three Partners are highly regarded in the life sciences industry for their thought leadership, passion for improving the lives of patients, and commitment to client service. Equally important, all three are highly regarded as role models and leaders in the firm, investing heavily in mentoring staff and reinforcing the firm’s culture. This move positions Health Advances for continued growth by bringing the Partner group to a total of 11 professionals.
Gary Gustavsen leads the Personalized Medicine Practice at Health Advances, where his work focuses on commercialization strategy, indication prioritization, pricing and reimbursement strategy, and business development opportunities for both diagnostic and therapeutic clients. Gary has been with Health Advances for nearly 12 years, rapidly advancing through the ranks from the entry level Analyst position. Prior to joining Health Advances, Gary worked at Brookhaven National Lab, Becton Dickinson, and OSI Pharmaceuticals. Gary received his BSE degree in Biomedical Engineering from Duke University and his MS degree in Biomedical Engineering from Stony Brook University.
Wyatt Gotbetter, with over 2 decades of experience in the life sciences industry, helps lead the Biopharma Practice and focuses on commercial growth and business development strategies for therapeutics companies. Wyatt joined Health Advances over 3 years ago after working at Boston Consulting Group (BCG), Biogen, and Boston Scientific in strategy, product and portfolio management and new product commercialization. He earned his BS degree in Economics & Policy Analysis and an MPA degree, including a certificate from the Sloan Graduate Program in Health Services Management, at Cornell University.
Andrew Matzkin has 15 years of experience as a strategy consultant in healthcare, including 8 years at Health Advances. He leads the Digital Health and Health IT Practice, working closely with companies and investors in digital health, health IT, and the life sciences to develop strategies for development and commercialization of digital solutions. His areas of emphasis include connected devices and diagnostics, patient monitoring, digital disease management, real world data, and big data analytics across a wide range of technologies and therapeutic areas. Prior to Health Advances, Andrew was a Consultant at Bain & Company and also worked at Novartis in the global cardiovascular-metabolic franchise. Andrew earned his BA degree, Phi Beta Kappa, from Yale University and an MBA from Harvard Business School, where he was honored as a Baker Scholar.
Health Advances Recognized as Hope Benefactor of BSCP
The Biomedical Science Careers Program (BSCP) held its annual Evening of Hope event to celebrate and perpetuate its mission of providing academically outstanding students with critical mentoring and financial aid. BSCP particularly seeks to assist students of color to ensure an ethnically diverse workforce in the life sciences and healthcare industries. Since its founding 20 years ago, the Massachusetts biotech community has nurtured this organization through contributions of funds and time. Health Advances is proud to have been a supporter throughout the organization’s history, this year recognized as a Hope Benefactor. Paula Ness Speers, Co-Founder and Managing Director, received an award from John Maraganore, PhD., CEO of Alnylam Pharmaceuticals and Co-Chair of the Evening of Hope event.
Kelly Cockerill, Andrew Funderburk, Sheela Hegde, and Julia Gaebler
While orphan drugs offer novel treatments for patients who previously had no options, the high price points they often command have resulted in restricted access by many European Health Technology Assessment (HTA) systems and intense discussions about how to determine their value. Against this backdrop, manufacturers are eager to understand how to value their innovation and collect sufficient evidence to support a price that appropriately reflects the improvement in clinical outcomes versus the standard of care. Patient prevalence is highly correlated with orphan drug pricing in Europe, highlighting the importance of budget impact to payer decision-making. With European pricing so complex and interrelated between countries, early understanding of the target orphan disease epidemiology and the product value proposition and price potential are all critical to optimize launch sequence decisions. To read the white paper, click on the header above.
Kelly Cockerill, Andrew Funderburk, Sheela Hegde
and Julia Gaebler
While orphan drugs offer novel treatments for patients who previously had no options, the high price points they often command have resulted in restricted access by many European Health Technology Assessment (HTA) systems and intense discussions about how to determine their value.
Against this backdrop, manufacturers are eager to understand how to value their innovation and collect sufficient evidence to support a price that appropriately reflects the improvement in clinical outcomes versus the standard of care. The white paper indicates that patient prevalence is highly correlated with orphan drug pricing in Europe, highlighting the importance of budget impact to payer decision-making.
Health Advances Kavitha Gnanasambandan authors a blog post on non-alcoholic fatty liver disease (NAFLD)
Outside of the rising aging population, another big public health concern is the increase in metabolic disorders such as obesity, diabetes, and non-alcoholic fatty liver disease (NAFLD). NAFLD represents a histopathological spectrum of liver diseases ranging from fat accumulation in liver (steatosis) to non-alcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and liver failure or liver cancer (hepatocellular carcinoma or HCC). NAFLD is estimated to affect 30% of adults in US. Pathogenesis of NAFLD is closely associated with obesity and diabetes and its prevalence has been rising in parallel with these two disorders. While adopting a healthy lifestyle could reverse NAFLD at the early stages such as steatosis, there is still a major unmet need for effective therapeutics at later stages of disease. To read the full post, please visit the Health Advances Blog
Partner Sheela Hegde hosted a biopharma industry panel on “Business Strategies that Advance Scientific Breakthrough” at the HBS Healthcare Conference in February. Executives from Moderna Therapeutics, Editas Medicine, and Blueprint Medicines shared their thoughts on how best to manage opportunity and risk during the pharmaceutical development process.
Over the past 15 years, the FDA and Congress developed several accelerated pathways to provide incentives for manufacturers to develop innovative new drugs to treat conditions with substantial unmet need. The objective of this white paper is to describe recent trends in the use of the FDA’s accelerated pathways and to examine the market advantage associated with these pathways, particularly in oncology.
Health Advances is proud to sponsor the Biomedical Science Careers Program’s (BSCP) Evening of Hope gala event as a “Hope Leader” on April 27, 2016. The event will honor two life science leaders and long-time friends of the firm, John Maraganore, PhD, CEO of Alnylam Pharmaceuticals, and Peter Slavin MD, President of Mass General Hospital.
BSCP was established in 1991 to increase the number of underrepresented minorities in the biomedical sciences and health professions. BSCP identifies academically outstanding minority students and trainees dreaming of a career in medicine, health care, science and biotechnology; and provides them with the information and support needed to achieve their goals through conferences, workshops, symposia, newsletters, scholarships and the BSCP Linkage Program.
The principal source of funds to support the critical mission of BSCP comes from sponsorships of Evening of Hope. As a result of the event, over 10,000 students and over 1,100 postdoctoral trainees and junior faculty have participated in BSCP programs. Several senior leaders of Health Advances will attend the event to celebrate BSCP’s accomplishments.
“Health Advances delivered a comprehensive evaluation of our key assets and helped to drive the creation of a focused business development strategy to accelerate the achievement of our scientific and business objectives.”