Allergy & Immunology
The understanding of human immunology has increased substantially over the past ten years. Scientific insights have revealed new pathways and targets and elucidated the complex interactions between the adaptive and innate immune systems. Furthermore, there is a greater appreciation of the interactions of the immune system with other systems, like the CNS or microbiome. All of this has led to a highly competitive development pipeline, requiring strong early planning to succeed in new and more complex treatment paradigms.
At Health Advances, our Immunology practice leaders partner with you to translate your particular scientific approach to immune-mediated diseases into clinical and commercial value inflections. The center point of many of our engagements is the scientific evaluation, clinical validation, and competitive assessment of new mechanisms in order to assess their eventual market potential.
Immunology Indications Assessed
Proprietary Indication Prioritization Databases
And other dedicated Immunology staff and resources
Allergy & Immunology Case Studies
A biopharma client engaged Health Advances to help maximize the value of a development stage asset with potential across a number of autoimmune indications. We developed a framework to assess the commercial attractiveness of the indications, as well as determine optimal product positioning and launch sequence. In addition, we devised a strategy to optimize pricing across six indications in six geographies. The client leveraged our insights to justify internal R&D investment priorities and negotiate a lucrative business development transaction.
A small biotech approached Health Advances to assess the feasibility of leveraging its antibody expertise to build a portfolio in Allergy. We characterized the Allergy therapeutic area landscape, identified the most attractive indications and mechanisms, and surfaced insights on critical success factors for portfolio development. The client used our recommendations to determine the most attractive path forward including which indications and mechanisms to pursue as well as business development opportunities to target.
A clinical-stage company asked Health Advances to help assess follow-on indications for its lead program with a novel mechanism to reduce inflammation. We analyzed key market issues including multi-indication pricing and value protection strategies. In addition, we developed peak revenue forecasts that optimized the commercial potential across all relevant indications. Our robust analysis directed the client’s lifecycle extension strategy.
A client with a robust pipeline of anti-inflammatory and anti-fibrotic assets needed support to develop a portfolio strategy in Inflammatory Bowel Disease (IBD). We developed and tested target product profiles (TPP) for each asset and determined their likely positioning in the future IBD treatment paradigm. Furthermore, we gathered insights on the likely evidence required for broad adoption and resultant clinical development paths. Our analysis supported the client’s co-positioning of several assets in IBD and informed the overall disease area strategy.
At the request of a biopharma client, Health Advances quantified the commercial opportunity for a cell therapy in lupus nephritis. We characterized the unmet needs, sized the addressable patient population, and mapped the logistical and market access challenges for the therapy. To determine the likely adoption, we conducted qualitative interviews as well as a survey with key stakeholders. The client used our robust revenue forecast to make R&D investment decisions on the asset.
Allergy & Immunology Leadership
- Biotech & Pharmaceuticals
- Diagnostics, Research Tools, & Precision Medicine
- MedTech
- Digital Health & Enterprise HIT
- Investors
News
7/23/2019
Launch of Health Advances Asia Limited Extends APAC Capability
The opening of Health Advances Asia Limited leverages the firm’s 20+ years of experience in the Asia/Pacific region to help both local and multi-national companies looking to expand their global footprint.
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2/6/2019
MedTech Expert, Tracy Walters, Promoted to Partner
We are delighted to announce the promotion of "Tracy Walters":/leadership/#tracy-walters to Partner of the firm. Tracy has excelled during her 12.5 years with the firm as one of the senior leaders of the MedTech Practice working with a wide variety of medical device clients ranging from small start-ups to some of the largest public companies in the industry. She is particularly accomplished in product forecasting, financial modeling, and international markets.
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11/20/2018
The Boston Globe Names Health Advances a Top Place to Work for 2018
Health Advances has been named one of the Top Places to Work in Massachusetts in the 11th annual employee-based survey project from The Boston Globe.
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7/11/2018
Health Advances Team Publishes Compelling Payer Budget Impact Analysis for Tactile Medical
"Julia Gaebler":/leadership/#julia-a-gaebler-phd, Partner, led a team (including Adam Cohen, Engagement Manger; Jessica Izhakoff, Consultant, and Laura Gullett, Senior Analyst) to assess the budget impact to a US commercial health plan of providing access to the Flexitouch (FLX) advanced pneumatic compression device to lymphedema patients with either comorbid chronic venous insufficiency or frequent infections.
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7/11/2018
Health Advances Team Publishes Compelling Economic Data for Tactile Medical
"Julia Gaebler":/leadership/#julia-a-gaebler-phd, Partner, led a team (including Michelle Lerman, Engagement Manager; Jessica Izhakoff, Senior Analyst, and Laura Gullett, Senior Analyst) to analyze the economic outcomes and medical resource use associated with Tactile Medical’s Flexitouch device vs. alternative therapies for phlebolymphedema patients.
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6/1/2018
Health Advances Celebrates 26 Years
In June of this year, Health Advances will celebrate its 26th Anniversary of supporting clients in the healthcare industry.
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6/1/2018
Health Advances’ San Francisco Office Celebrates Ten Years
Health Advances recently celebrated the 10th anniversary of our San Francisco office. The success and rapid growth of this office reflect the strong relationships we have built with clients across biopharma, diagnostics, medical devices, digital health, and private equity.
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2/15/2018
Health Advances Hires Three Vice Presidents
Darcy Krzynowek, Balazs Felcsuti, and Ruggero Rossi recently joined Health Advances as Vice Presidents in the Boston area office. “We are delighted to be able to attract these three talented industry leaders to complement our management team. Each of them brings unique skills and experiences that will expand our offerings to clients and enrich our consulting teams,” explained Paula Ness Speers, Co-Founder of Health Advances.
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1/18/2018
Winners of the Boston Pediatric Device Strategic Partner Challenge Unveiled
"The Boston Pediatric Device Strategic Partner Challenge(BPDC)":https://www.bostonpdc.org/ attracted an eclectic applicant pool of entrepreneurs and innovators from around the globe.
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9/11/2017
Health Advances Partners with Boston Children’s Hospital to Launch Pediatric Device Challenge
Health Advances is proud to be a provider partner to the Boston Pediatric Device Strategic Partner Challenge! This Challenge addresses the critical need for pediatric device development, and we are thrilled to partner with the Boston Pediatric Device Consortium and the Innovation & Digital Health Accelerator at Boston Children’s Hospital to promote this exciting opportunity – see full press release "here":http://www.prnewswire.com/news-releases/boston-childrens-hospital-and-boston-pediatric-device-consortium-launch-pediatric-medical-device-challenge-300517063.html.
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4/19/2017
Health Advances Honored by Forbes as One of America’s Best Management Consulting Firms
Health Advances has been honored by Forbes as One of America’s Best Management Consulting Firms for 2017.
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2/16/2017
Health Advances Celebrates 25 Years
In June of this year, Health Advances will celebrate its 25th Anniversary of supporting clients in the healthcare industry. We are proud of the fact that the company has stayed true to its initial vision of helping clients commercialize meaningful new products and services that improve the quality and cost-effectiveness of healthcare. We are also proud of the talented employees and alumni/ae who have helped build the firm’s reputation for responsiveness, insight and integrity.
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